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Hampton Research Corp jeffamine ed 2001 ph 7 0
Jeffamine Ed 2001 Ph 7 0, supplied by Hampton Research Corp, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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jeffamine ed 2001 ph 7 0 - by Bioz Stars, 2026-09
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Incubation:

Article Title: Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
Article Snippet: Diffraction-quality crystals of the DSM25/NKG2D SCD complex were obtained from drops containing 10 mg/mL protein in PNE by hanging-drop vapor diffusion over wells containing 100 mM HEPES (pH 7.2) and 35% w/w Jeffamine ED-2001 (Hampton Research #HR2-597).

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the former mixing solution, the Zn 2+ -bound EFhd1 core domain (EFhd1 Zn ) crystals were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 2.5 m M ZnSO 4 and 25%( w / v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
Article Snippet: Crystals were obtained using a reservoir solution containing 0.1 M HEPES-NaOH (pH 7.5), 5 mM ZnSO 4 , and 25% (w/ v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, Peptides, and Recombinant Proteins CD96-D1 This paper N/A Necl-5 (Deuss et al., 2017) N/A Nectin-2 (Deuss et al., 2017) N/A DMEM High Glucose SOBS Media and Prep Services (Monash University) N/A Penicillin-Streptomycin-Glutamine (100X) Gibco Cat# 10378016 Glutamax (100X) Gibco Cat# 35050061 Non-essential Amino Acids (100X) Gibco Cat#11140050 FCS Sigma-Aldrich Cat# F9423 Insect-XPRESS medium Lonza Cat# 12-730Q Polyethyleneimine Sigma-Aldrich Cat# 408727 Cellfectin II Invitrogen Cat# 10362100 Endo H NEB Cat# P0702S D-biotin Sigma-Aldrich Cat# 47868 P20 GE Healthcare Cat# BR100054 Jeffamine ED-2001 Hampton Research Cat# HR2-597 HEPES Sigma-Aldrich Cat# H4034 PEG400 Sigma-Aldrich Cat# 202398 GoTaq Green master mix Promega Cat# M7123 Critical Commercial Assays Streptavidin coated chips GE Healthcare Cat# BR100032 HisTrap columns GE Healthcare Cat# 17-5248-02 Superdex200 16/600 column GE Healthcare Cat# 28989335 Superdex75 16/600 column GE Healthcare Cat# 28989333 Cogent M1 Tangential flow filtration Millipore Cat# CM06230 Pellicon 3 Cassette with Ultracel PLC Membrane Millipore Cat# P3C 010 C01 GenElute Plasmid Miniprep Kit Sigma-Aldrich Cat# PLN350 GenElute HP Plasmid Gigaprep Kit Sigma-Aldrich Cat# NA0800-1KT Qiagen Plasmid Mini kit Qiagen Cat# 12125 Mastercycler Nexus Gradient PCR Eppendorf Cat# 6331000068 Deposited Data Co-crystal structure of CD96-D1:necl-5 This paper PDB: 6ARQ Crystal structure of necl-5 (Harrison et al., 2012) PDB: 4FQP Experimental Models: Cell Lines Human: HEK293S GnTi- ATCC (In vitro Technologies) Cat# CRL-3022; RRID: CVCL_A785 Hi5 insect cells Life Technologies Cat# B855-02 Sf9 insect cells Thermo Fischer Scientific Cat# 11496-015 DH10Bac E.coli cells Thermo Fischer Scientific Cat# 10361-012 OneShot TOP10 chemical competent E.coli cells Thermo Fischer Scientific Cat# C404003 Recombinant DNA pHLSec (Aricescu et al., 2006) N/A pFastbac Thermo Fisher Scientific Cat# 10712-024 Synthetic genes for CD96 D1, nectin-2 and necl-5 IDT N/A (Continued on next page) Structure 27, 1–10.e1–e3, February 5, 2019 e1

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca 2+ -bound EFhd1 core domain (EFhd1 Ca ) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 m M ZnSO 4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Biochemical and crystallographic studies of l,d -transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate
Article Snippet: Ldt Mt2 wild type or Ldt Mt2 C354S (Δ1-55; with the N-terminal His Tag removed, in 50 mM tris, pH 8.0, 100 mM NaCl) was incubated with substrate 1 or for 30 minutes on ice, and then crystallised using a well solution consisting of 0.1 M HEPES, pH 7.0, and 25% ( v / v ) Jeffamine ED-2001 pH 7.0 (identified from the JCSG Plus TM crystallisation screen, Hampton Research), using sitting drop vapour diffusion crystallisation plates (low reservoir Intelli-Plate 93-3), with 1 μL of protein-substrate solution and 1 μL of well solution.

Article Title: Structural and biochemical insights into Zn<sup>2+</sup>-bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca2+-bound EFhd1 core domain (EFhd1Ca) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 mM ZnSO4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Structure and Function of Non-Native Metal Clusters in Human Arginase I
Article Snippet: Prepared solutions of 50% (w/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) and 30% (v/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) were purchased from Hampton Research (Aliso Viejo, CA).

Diffusion-based Assay:

Article Title: Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
Article Snippet: Diffraction-quality crystals of the DSM25/NKG2D SCD complex were obtained from drops containing 10 mg/mL protein in PNE by hanging-drop vapor diffusion over wells containing 100 mM HEPES (pH 7.2) and 35% w/w Jeffamine ED-2001 (Hampton Research #HR2-597).

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the former mixing solution, the Zn 2+ -bound EFhd1 core domain (EFhd1 Zn ) crystals were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 2.5 m M ZnSO 4 and 25%( w / v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
Article Snippet: Crystals were obtained using a reservoir solution containing 0.1 M HEPES-NaOH (pH 7.5), 5 mM ZnSO 4 , and 25% (w/ v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, Peptides, and Recombinant Proteins CD96-D1 This paper N/A Necl-5 (Deuss et al., 2017) N/A Nectin-2 (Deuss et al., 2017) N/A DMEM High Glucose SOBS Media and Prep Services (Monash University) N/A Penicillin-Streptomycin-Glutamine (100X) Gibco Cat# 10378016 Glutamax (100X) Gibco Cat# 35050061 Non-essential Amino Acids (100X) Gibco Cat#11140050 FCS Sigma-Aldrich Cat# F9423 Insect-XPRESS medium Lonza Cat# 12-730Q Polyethyleneimine Sigma-Aldrich Cat# 408727 Cellfectin II Invitrogen Cat# 10362100 Endo H NEB Cat# P0702S D-biotin Sigma-Aldrich Cat# 47868 P20 GE Healthcare Cat# BR100054 Jeffamine ED-2001 Hampton Research Cat# HR2-597 HEPES Sigma-Aldrich Cat# H4034 PEG400 Sigma-Aldrich Cat# 202398 GoTaq Green master mix Promega Cat# M7123 Critical Commercial Assays Streptavidin coated chips GE Healthcare Cat# BR100032 HisTrap columns GE Healthcare Cat# 17-5248-02 Superdex200 16/600 column GE Healthcare Cat# 28989335 Superdex75 16/600 column GE Healthcare Cat# 28989333 Cogent M1 Tangential flow filtration Millipore Cat# CM06230 Pellicon 3 Cassette with Ultracel PLC Membrane Millipore Cat# P3C 010 C01 GenElute Plasmid Miniprep Kit Sigma-Aldrich Cat# PLN350 GenElute HP Plasmid Gigaprep Kit Sigma-Aldrich Cat# NA0800-1KT Qiagen Plasmid Mini kit Qiagen Cat# 12125 Mastercycler Nexus Gradient PCR Eppendorf Cat# 6331000068 Deposited Data Co-crystal structure of CD96-D1:necl-5 This paper PDB: 6ARQ Crystal structure of necl-5 (Harrison et al., 2012) PDB: 4FQP Experimental Models: Cell Lines Human: HEK293S GnTi- ATCC (In vitro Technologies) Cat# CRL-3022; RRID: CVCL_A785 Hi5 insect cells Life Technologies Cat# B855-02 Sf9 insect cells Thermo Fischer Scientific Cat# 11496-015 DH10Bac E.coli cells Thermo Fischer Scientific Cat# 10361-012 OneShot TOP10 chemical competent E.coli cells Thermo Fischer Scientific Cat# C404003 Recombinant DNA pHLSec (Aricescu et al., 2006) N/A pFastbac Thermo Fisher Scientific Cat# 10712-024 Synthetic genes for CD96 D1, nectin-2 and necl-5 IDT N/A (Continued on next page) Structure 27, 1–10.e1–e3, February 5, 2019 e1

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca 2+ -bound EFhd1 core domain (EFhd1 Ca ) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 m M ZnSO 4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Biochemical and crystallographic studies of l,d -transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate
Article Snippet: Ldt Mt2 wild type or Ldt Mt2 C354S (Δ1-55; with the N-terminal His Tag removed, in 50 mM tris, pH 8.0, 100 mM NaCl) was incubated with substrate 1 or for 30 minutes on ice, and then crystallised using a well solution consisting of 0.1 M HEPES, pH 7.0, and 25% ( v / v ) Jeffamine ED-2001 pH 7.0 (identified from the JCSG Plus TM crystallisation screen, Hampton Research), using sitting drop vapour diffusion crystallisation plates (low reservoir Intelli-Plate 93-3), with 1 μL of protein-substrate solution and 1 μL of well solution.

Article Title: Structural and biochemical insights into Zn<sup>2+</sup>-bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca2+-bound EFhd1 core domain (EFhd1Ca) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 mM ZnSO4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Structure and Function of Non-Native Metal Clusters in Human Arginase I
Article Snippet: Prepared solutions of 50% (w/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) and 30% (v/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) were purchased from Hampton Research (Aliso Viejo, CA).

Recombinant:

Article Title: Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
Article Snippet: Diffraction-quality crystals of the DSM25/NKG2D SCD complex were obtained from drops containing 10 mg/mL protein in PNE by hanging-drop vapor diffusion over wells containing 100 mM HEPES (pH 7.2) and 35% w/w Jeffamine ED-2001 (Hampton Research #HR2-597).

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the former mixing solution, the Zn 2+ -bound EFhd1 core domain (EFhd1 Zn ) crystals were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 2.5 m M ZnSO 4 and 25%( w / v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
Article Snippet: Crystals were obtained using a reservoir solution containing 0.1 M HEPES-NaOH (pH 7.5), 5 mM ZnSO 4 , and 25% (w/ v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, Peptides, and Recombinant Proteins CD96-D1 This paper N/A Necl-5 (Deuss et al., 2017) N/A Nectin-2 (Deuss et al., 2017) N/A DMEM High Glucose SOBS Media and Prep Services (Monash University) N/A Penicillin-Streptomycin-Glutamine (100X) Gibco Cat# 10378016 Glutamax (100X) Gibco Cat# 35050061 Non-essential Amino Acids (100X) Gibco Cat#11140050 FCS Sigma-Aldrich Cat# F9423 Insect-XPRESS medium Lonza Cat# 12-730Q Polyethyleneimine Sigma-Aldrich Cat# 408727 Cellfectin II Invitrogen Cat# 10362100 Endo H NEB Cat# P0702S D-biotin Sigma-Aldrich Cat# 47868 P20 GE Healthcare Cat# BR100054 Jeffamine ED-2001 Hampton Research Cat# HR2-597 HEPES Sigma-Aldrich Cat# H4034 PEG400 Sigma-Aldrich Cat# 202398 GoTaq Green master mix Promega Cat# M7123 Critical Commercial Assays Streptavidin coated chips GE Healthcare Cat# BR100032 HisTrap columns GE Healthcare Cat# 17-5248-02 Superdex200 16/600 column GE Healthcare Cat# 28989335 Superdex75 16/600 column GE Healthcare Cat# 28989333 Cogent M1 Tangential flow filtration Millipore Cat# CM06230 Pellicon 3 Cassette with Ultracel PLC Membrane Millipore Cat# P3C 010 C01 GenElute Plasmid Miniprep Kit Sigma-Aldrich Cat# PLN350 GenElute HP Plasmid Gigaprep Kit Sigma-Aldrich Cat# NA0800-1KT Qiagen Plasmid Mini kit Qiagen Cat# 12125 Mastercycler Nexus Gradient PCR Eppendorf Cat# 6331000068 Deposited Data Co-crystal structure of CD96-D1:necl-5 This paper PDB: 6ARQ Crystal structure of necl-5 (Harrison et al., 2012) PDB: 4FQP Experimental Models: Cell Lines Human: HEK293S GnTi- ATCC (In vitro Technologies) Cat# CRL-3022; RRID: CVCL_A785 Hi5 insect cells Life Technologies Cat# B855-02 Sf9 insect cells Thermo Fischer Scientific Cat# 11496-015 DH10Bac E.coli cells Thermo Fischer Scientific Cat# 10361-012 OneShot TOP10 chemical competent E.coli cells Thermo Fischer Scientific Cat# C404003 Recombinant DNA pHLSec (Aricescu et al., 2006) N/A pFastbac Thermo Fisher Scientific Cat# 10712-024 Synthetic genes for CD96 D1, nectin-2 and necl-5 IDT N/A (Continued on next page) Structure 27, 1–10.e1–e3, February 5, 2019 e1

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca 2+ -bound EFhd1 core domain (EFhd1 Ca ) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 m M ZnSO 4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Biochemical and crystallographic studies of l,d -transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate
Article Snippet: Ldt Mt2 wild type or Ldt Mt2 C354S (Δ1-55; with the N-terminal His Tag removed, in 50 mM tris, pH 8.0, 100 mM NaCl) was incubated with substrate 1 or for 30 minutes on ice, and then crystallised using a well solution consisting of 0.1 M HEPES, pH 7.0, and 25% ( v / v ) Jeffamine ED-2001 pH 7.0 (identified from the JCSG Plus TM crystallisation screen, Hampton Research), using sitting drop vapour diffusion crystallisation plates (low reservoir Intelli-Plate 93-3), with 1 μL of protein-substrate solution and 1 μL of well solution.

Article Title: Structural and biochemical insights into Zn<sup>2+</sup>-bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca2+-bound EFhd1 core domain (EFhd1Ca) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 mM ZnSO4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Structure and Function of Non-Native Metal Clusters in Human Arginase I
Article Snippet: Prepared solutions of 50% (w/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) and 30% (v/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) were purchased from Hampton Research (Aliso Viejo, CA).

Filtration:

Article Title: Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
Article Snippet: Diffraction-quality crystals of the DSM25/NKG2D SCD complex were obtained from drops containing 10 mg/mL protein in PNE by hanging-drop vapor diffusion over wells containing 100 mM HEPES (pH 7.2) and 35% w/w Jeffamine ED-2001 (Hampton Research #HR2-597).

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the former mixing solution, the Zn 2+ -bound EFhd1 core domain (EFhd1 Zn ) crystals were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 2.5 m M ZnSO 4 and 25%( w / v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
Article Snippet: Crystals were obtained using a reservoir solution containing 0.1 M HEPES-NaOH (pH 7.5), 5 mM ZnSO 4 , and 25% (w/ v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, Peptides, and Recombinant Proteins CD96-D1 This paper N/A Necl-5 (Deuss et al., 2017) N/A Nectin-2 (Deuss et al., 2017) N/A DMEM High Glucose SOBS Media and Prep Services (Monash University) N/A Penicillin-Streptomycin-Glutamine (100X) Gibco Cat# 10378016 Glutamax (100X) Gibco Cat# 35050061 Non-essential Amino Acids (100X) Gibco Cat#11140050 FCS Sigma-Aldrich Cat# F9423 Insect-XPRESS medium Lonza Cat# 12-730Q Polyethyleneimine Sigma-Aldrich Cat# 408727 Cellfectin II Invitrogen Cat# 10362100 Endo H NEB Cat# P0702S D-biotin Sigma-Aldrich Cat# 47868 P20 GE Healthcare Cat# BR100054 Jeffamine ED-2001 Hampton Research Cat# HR2-597 HEPES Sigma-Aldrich Cat# H4034 PEG400 Sigma-Aldrich Cat# 202398 GoTaq Green master mix Promega Cat# M7123 Critical Commercial Assays Streptavidin coated chips GE Healthcare Cat# BR100032 HisTrap columns GE Healthcare Cat# 17-5248-02 Superdex200 16/600 column GE Healthcare Cat# 28989335 Superdex75 16/600 column GE Healthcare Cat# 28989333 Cogent M1 Tangential flow filtration Millipore Cat# CM06230 Pellicon 3 Cassette with Ultracel PLC Membrane Millipore Cat# P3C 010 C01 GenElute Plasmid Miniprep Kit Sigma-Aldrich Cat# PLN350 GenElute HP Plasmid Gigaprep Kit Sigma-Aldrich Cat# NA0800-1KT Qiagen Plasmid Mini kit Qiagen Cat# 12125 Mastercycler Nexus Gradient PCR Eppendorf Cat# 6331000068 Deposited Data Co-crystal structure of CD96-D1:necl-5 This paper PDB: 6ARQ Crystal structure of necl-5 (Harrison et al., 2012) PDB: 4FQP Experimental Models: Cell Lines Human: HEK293S GnTi- ATCC (In vitro Technologies) Cat# CRL-3022; RRID: CVCL_A785 Hi5 insect cells Life Technologies Cat# B855-02 Sf9 insect cells Thermo Fischer Scientific Cat# 11496-015 DH10Bac E.coli cells Thermo Fischer Scientific Cat# 10361-012 OneShot TOP10 chemical competent E.coli cells Thermo Fischer Scientific Cat# C404003 Recombinant DNA pHLSec (Aricescu et al., 2006) N/A pFastbac Thermo Fisher Scientific Cat# 10712-024 Synthetic genes for CD96 D1, nectin-2 and necl-5 IDT N/A (Continued on next page) Structure 27, 1–10.e1–e3, February 5, 2019 e1

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca 2+ -bound EFhd1 core domain (EFhd1 Ca ) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 m M ZnSO 4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Biochemical and crystallographic studies of l,d -transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate
Article Snippet: Ldt Mt2 wild type or Ldt Mt2 C354S (Δ1-55; with the N-terminal His Tag removed, in 50 mM tris, pH 8.0, 100 mM NaCl) was incubated with substrate 1 or for 30 minutes on ice, and then crystallised using a well solution consisting of 0.1 M HEPES, pH 7.0, and 25% ( v / v ) Jeffamine ED-2001 pH 7.0 (identified from the JCSG Plus TM crystallisation screen, Hampton Research), using sitting drop vapour diffusion crystallisation plates (low reservoir Intelli-Plate 93-3), with 1 μL of protein-substrate solution and 1 μL of well solution.

Article Title: Structural and biochemical insights into Zn<sup>2+</sup>-bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca2+-bound EFhd1 core domain (EFhd1Ca) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 mM ZnSO4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Structure and Function of Non-Native Metal Clusters in Human Arginase I
Article Snippet: Prepared solutions of 50% (w/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) and 30% (v/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) were purchased from Hampton Research (Aliso Viejo, CA).

Planar Chromatography:

Article Title: Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
Article Snippet: Diffraction-quality crystals of the DSM25/NKG2D SCD complex were obtained from drops containing 10 mg/mL protein in PNE by hanging-drop vapor diffusion over wells containing 100 mM HEPES (pH 7.2) and 35% w/w Jeffamine ED-2001 (Hampton Research #HR2-597).

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the former mixing solution, the Zn 2+ -bound EFhd1 core domain (EFhd1 Zn ) crystals were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 2.5 m M ZnSO 4 and 25%( w / v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
Article Snippet: Crystals were obtained using a reservoir solution containing 0.1 M HEPES-NaOH (pH 7.5), 5 mM ZnSO 4 , and 25% (w/ v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, Peptides, and Recombinant Proteins CD96-D1 This paper N/A Necl-5 (Deuss et al., 2017) N/A Nectin-2 (Deuss et al., 2017) N/A DMEM High Glucose SOBS Media and Prep Services (Monash University) N/A Penicillin-Streptomycin-Glutamine (100X) Gibco Cat# 10378016 Glutamax (100X) Gibco Cat# 35050061 Non-essential Amino Acids (100X) Gibco Cat#11140050 FCS Sigma-Aldrich Cat# F9423 Insect-XPRESS medium Lonza Cat# 12-730Q Polyethyleneimine Sigma-Aldrich Cat# 408727 Cellfectin II Invitrogen Cat# 10362100 Endo H NEB Cat# P0702S D-biotin Sigma-Aldrich Cat# 47868 P20 GE Healthcare Cat# BR100054 Jeffamine ED-2001 Hampton Research Cat# HR2-597 HEPES Sigma-Aldrich Cat# H4034 PEG400 Sigma-Aldrich Cat# 202398 GoTaq Green master mix Promega Cat# M7123 Critical Commercial Assays Streptavidin coated chips GE Healthcare Cat# BR100032 HisTrap columns GE Healthcare Cat# 17-5248-02 Superdex200 16/600 column GE Healthcare Cat# 28989335 Superdex75 16/600 column GE Healthcare Cat# 28989333 Cogent M1 Tangential flow filtration Millipore Cat# CM06230 Pellicon 3 Cassette with Ultracel PLC Membrane Millipore Cat# P3C 010 C01 GenElute Plasmid Miniprep Kit Sigma-Aldrich Cat# PLN350 GenElute HP Plasmid Gigaprep Kit Sigma-Aldrich Cat# NA0800-1KT Qiagen Plasmid Mini kit Qiagen Cat# 12125 Mastercycler Nexus Gradient PCR Eppendorf Cat# 6331000068 Deposited Data Co-crystal structure of CD96-D1:necl-5 This paper PDB: 6ARQ Crystal structure of necl-5 (Harrison et al., 2012) PDB: 4FQP Experimental Models: Cell Lines Human: HEK293S GnTi- ATCC (In vitro Technologies) Cat# CRL-3022; RRID: CVCL_A785 Hi5 insect cells Life Technologies Cat# B855-02 Sf9 insect cells Thermo Fischer Scientific Cat# 11496-015 DH10Bac E.coli cells Thermo Fischer Scientific Cat# 10361-012 OneShot TOP10 chemical competent E.coli cells Thermo Fischer Scientific Cat# C404003 Recombinant DNA pHLSec (Aricescu et al., 2006) N/A pFastbac Thermo Fisher Scientific Cat# 10712-024 Synthetic genes for CD96 D1, nectin-2 and necl-5 IDT N/A (Continued on next page) Structure 27, 1–10.e1–e3, February 5, 2019 e1

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca 2+ -bound EFhd1 core domain (EFhd1 Ca ) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 m M ZnSO 4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Biochemical and crystallographic studies of l,d -transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate
Article Snippet: Ldt Mt2 wild type or Ldt Mt2 C354S (Δ1-55; with the N-terminal His Tag removed, in 50 mM tris, pH 8.0, 100 mM NaCl) was incubated with substrate 1 or for 30 minutes on ice, and then crystallised using a well solution consisting of 0.1 M HEPES, pH 7.0, and 25% ( v / v ) Jeffamine ED-2001 pH 7.0 (identified from the JCSG Plus TM crystallisation screen, Hampton Research), using sitting drop vapour diffusion crystallisation plates (low reservoir Intelli-Plate 93-3), with 1 μL of protein-substrate solution and 1 μL of well solution.

Article Title: Structural and biochemical insights into Zn<sup>2+</sup>-bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca2+-bound EFhd1 core domain (EFhd1Ca) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 mM ZnSO4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Structure and Function of Non-Native Metal Clusters in Human Arginase I
Article Snippet: Prepared solutions of 50% (w/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) and 30% (v/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) were purchased from Hampton Research (Aliso Viejo, CA).

Membrane:

Article Title: Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
Article Snippet: Diffraction-quality crystals of the DSM25/NKG2D SCD complex were obtained from drops containing 10 mg/mL protein in PNE by hanging-drop vapor diffusion over wells containing 100 mM HEPES (pH 7.2) and 35% w/w Jeffamine ED-2001 (Hampton Research #HR2-597).

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the former mixing solution, the Zn 2+ -bound EFhd1 core domain (EFhd1 Zn ) crystals were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 2.5 m M ZnSO 4 and 25%( w / v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
Article Snippet: Crystals were obtained using a reservoir solution containing 0.1 M HEPES-NaOH (pH 7.5), 5 mM ZnSO 4 , and 25% (w/ v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, Peptides, and Recombinant Proteins CD96-D1 This paper N/A Necl-5 (Deuss et al., 2017) N/A Nectin-2 (Deuss et al., 2017) N/A DMEM High Glucose SOBS Media and Prep Services (Monash University) N/A Penicillin-Streptomycin-Glutamine (100X) Gibco Cat# 10378016 Glutamax (100X) Gibco Cat# 35050061 Non-essential Amino Acids (100X) Gibco Cat#11140050 FCS Sigma-Aldrich Cat# F9423 Insect-XPRESS medium Lonza Cat# 12-730Q Polyethyleneimine Sigma-Aldrich Cat# 408727 Cellfectin II Invitrogen Cat# 10362100 Endo H NEB Cat# P0702S D-biotin Sigma-Aldrich Cat# 47868 P20 GE Healthcare Cat# BR100054 Jeffamine ED-2001 Hampton Research Cat# HR2-597 HEPES Sigma-Aldrich Cat# H4034 PEG400 Sigma-Aldrich Cat# 202398 GoTaq Green master mix Promega Cat# M7123 Critical Commercial Assays Streptavidin coated chips GE Healthcare Cat# BR100032 HisTrap columns GE Healthcare Cat# 17-5248-02 Superdex200 16/600 column GE Healthcare Cat# 28989335 Superdex75 16/600 column GE Healthcare Cat# 28989333 Cogent M1 Tangential flow filtration Millipore Cat# CM06230 Pellicon 3 Cassette with Ultracel PLC Membrane Millipore Cat# P3C 010 C01 GenElute Plasmid Miniprep Kit Sigma-Aldrich Cat# PLN350 GenElute HP Plasmid Gigaprep Kit Sigma-Aldrich Cat# NA0800-1KT Qiagen Plasmid Mini kit Qiagen Cat# 12125 Mastercycler Nexus Gradient PCR Eppendorf Cat# 6331000068 Deposited Data Co-crystal structure of CD96-D1:necl-5 This paper PDB: 6ARQ Crystal structure of necl-5 (Harrison et al., 2012) PDB: 4FQP Experimental Models: Cell Lines Human: HEK293S GnTi- ATCC (In vitro Technologies) Cat# CRL-3022; RRID: CVCL_A785 Hi5 insect cells Life Technologies Cat# B855-02 Sf9 insect cells Thermo Fischer Scientific Cat# 11496-015 DH10Bac E.coli cells Thermo Fischer Scientific Cat# 10361-012 OneShot TOP10 chemical competent E.coli cells Thermo Fischer Scientific Cat# C404003 Recombinant DNA pHLSec (Aricescu et al., 2006) N/A pFastbac Thermo Fisher Scientific Cat# 10712-024 Synthetic genes for CD96 D1, nectin-2 and necl-5 IDT N/A (Continued on next page) Structure 27, 1–10.e1–e3, February 5, 2019 e1

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca 2+ -bound EFhd1 core domain (EFhd1 Ca ) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 m M ZnSO 4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Biochemical and crystallographic studies of l,d -transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate
Article Snippet: Ldt Mt2 wild type or Ldt Mt2 C354S (Δ1-55; with the N-terminal His Tag removed, in 50 mM tris, pH 8.0, 100 mM NaCl) was incubated with substrate 1 or for 30 minutes on ice, and then crystallised using a well solution consisting of 0.1 M HEPES, pH 7.0, and 25% ( v / v ) Jeffamine ED-2001 pH 7.0 (identified from the JCSG Plus TM crystallisation screen, Hampton Research), using sitting drop vapour diffusion crystallisation plates (low reservoir Intelli-Plate 93-3), with 1 μL of protein-substrate solution and 1 μL of well solution.

Article Title: Structural and biochemical insights into Zn<sup>2+</sup>-bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca2+-bound EFhd1 core domain (EFhd1Ca) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 mM ZnSO4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Structure and Function of Non-Native Metal Clusters in Human Arginase I
Article Snippet: Prepared solutions of 50% (w/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) and 30% (v/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) were purchased from Hampton Research (Aliso Viejo, CA).

Plasmid Preparation:

Article Title: Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
Article Snippet: Diffraction-quality crystals of the DSM25/NKG2D SCD complex were obtained from drops containing 10 mg/mL protein in PNE by hanging-drop vapor diffusion over wells containing 100 mM HEPES (pH 7.2) and 35% w/w Jeffamine ED-2001 (Hampton Research #HR2-597).

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the former mixing solution, the Zn 2+ -bound EFhd1 core domain (EFhd1 Zn ) crystals were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 2.5 m M ZnSO 4 and 25%( w / v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
Article Snippet: Crystals were obtained using a reservoir solution containing 0.1 M HEPES-NaOH (pH 7.5), 5 mM ZnSO 4 , and 25% (w/ v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, Peptides, and Recombinant Proteins CD96-D1 This paper N/A Necl-5 (Deuss et al., 2017) N/A Nectin-2 (Deuss et al., 2017) N/A DMEM High Glucose SOBS Media and Prep Services (Monash University) N/A Penicillin-Streptomycin-Glutamine (100X) Gibco Cat# 10378016 Glutamax (100X) Gibco Cat# 35050061 Non-essential Amino Acids (100X) Gibco Cat#11140050 FCS Sigma-Aldrich Cat# F9423 Insect-XPRESS medium Lonza Cat# 12-730Q Polyethyleneimine Sigma-Aldrich Cat# 408727 Cellfectin II Invitrogen Cat# 10362100 Endo H NEB Cat# P0702S D-biotin Sigma-Aldrich Cat# 47868 P20 GE Healthcare Cat# BR100054 Jeffamine ED-2001 Hampton Research Cat# HR2-597 HEPES Sigma-Aldrich Cat# H4034 PEG400 Sigma-Aldrich Cat# 202398 GoTaq Green master mix Promega Cat# M7123 Critical Commercial Assays Streptavidin coated chips GE Healthcare Cat# BR100032 HisTrap columns GE Healthcare Cat# 17-5248-02 Superdex200 16/600 column GE Healthcare Cat# 28989335 Superdex75 16/600 column GE Healthcare Cat# 28989333 Cogent M1 Tangential flow filtration Millipore Cat# CM06230 Pellicon 3 Cassette with Ultracel PLC Membrane Millipore Cat# P3C 010 C01 GenElute Plasmid Miniprep Kit Sigma-Aldrich Cat# PLN350 GenElute HP Plasmid Gigaprep Kit Sigma-Aldrich Cat# NA0800-1KT Qiagen Plasmid Mini kit Qiagen Cat# 12125 Mastercycler Nexus Gradient PCR Eppendorf Cat# 6331000068 Deposited Data Co-crystal structure of CD96-D1:necl-5 This paper PDB: 6ARQ Crystal structure of necl-5 (Harrison et al., 2012) PDB: 4FQP Experimental Models: Cell Lines Human: HEK293S GnTi- ATCC (In vitro Technologies) Cat# CRL-3022; RRID: CVCL_A785 Hi5 insect cells Life Technologies Cat# B855-02 Sf9 insect cells Thermo Fischer Scientific Cat# 11496-015 DH10Bac E.coli cells Thermo Fischer Scientific Cat# 10361-012 OneShot TOP10 chemical competent E.coli cells Thermo Fischer Scientific Cat# C404003 Recombinant DNA pHLSec (Aricescu et al., 2006) N/A pFastbac Thermo Fisher Scientific Cat# 10712-024 Synthetic genes for CD96 D1, nectin-2 and necl-5 IDT N/A (Continued on next page) Structure 27, 1–10.e1–e3, February 5, 2019 e1

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca 2+ -bound EFhd1 core domain (EFhd1 Ca ) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 m M ZnSO 4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Biochemical and crystallographic studies of l,d -transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate
Article Snippet: Ldt Mt2 wild type or Ldt Mt2 C354S (Δ1-55; with the N-terminal His Tag removed, in 50 mM tris, pH 8.0, 100 mM NaCl) was incubated with substrate 1 or for 30 minutes on ice, and then crystallised using a well solution consisting of 0.1 M HEPES, pH 7.0, and 25% ( v / v ) Jeffamine ED-2001 pH 7.0 (identified from the JCSG Plus TM crystallisation screen, Hampton Research), using sitting drop vapour diffusion crystallisation plates (low reservoir Intelli-Plate 93-3), with 1 μL of protein-substrate solution and 1 μL of well solution.

Article Title: Structural and biochemical insights into Zn<sup>2+</sup>-bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca2+-bound EFhd1 core domain (EFhd1Ca) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 mM ZnSO4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Structure and Function of Non-Native Metal Clusters in Human Arginase I
Article Snippet: Prepared solutions of 50% (w/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) and 30% (v/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) were purchased from Hampton Research (Aliso Viejo, CA).

Polymerase Chain Reaction:

Article Title: Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
Article Snippet: Diffraction-quality crystals of the DSM25/NKG2D SCD complex were obtained from drops containing 10 mg/mL protein in PNE by hanging-drop vapor diffusion over wells containing 100 mM HEPES (pH 7.2) and 35% w/w Jeffamine ED-2001 (Hampton Research #HR2-597).

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the former mixing solution, the Zn 2+ -bound EFhd1 core domain (EFhd1 Zn ) crystals were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 2.5 m M ZnSO 4 and 25%( w / v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
Article Snippet: Crystals were obtained using a reservoir solution containing 0.1 M HEPES-NaOH (pH 7.5), 5 mM ZnSO 4 , and 25% (w/ v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, Peptides, and Recombinant Proteins CD96-D1 This paper N/A Necl-5 (Deuss et al., 2017) N/A Nectin-2 (Deuss et al., 2017) N/A DMEM High Glucose SOBS Media and Prep Services (Monash University) N/A Penicillin-Streptomycin-Glutamine (100X) Gibco Cat# 10378016 Glutamax (100X) Gibco Cat# 35050061 Non-essential Amino Acids (100X) Gibco Cat#11140050 FCS Sigma-Aldrich Cat# F9423 Insect-XPRESS medium Lonza Cat# 12-730Q Polyethyleneimine Sigma-Aldrich Cat# 408727 Cellfectin II Invitrogen Cat# 10362100 Endo H NEB Cat# P0702S D-biotin Sigma-Aldrich Cat# 47868 P20 GE Healthcare Cat# BR100054 Jeffamine ED-2001 Hampton Research Cat# HR2-597 HEPES Sigma-Aldrich Cat# H4034 PEG400 Sigma-Aldrich Cat# 202398 GoTaq Green master mix Promega Cat# M7123 Critical Commercial Assays Streptavidin coated chips GE Healthcare Cat# BR100032 HisTrap columns GE Healthcare Cat# 17-5248-02 Superdex200 16/600 column GE Healthcare Cat# 28989335 Superdex75 16/600 column GE Healthcare Cat# 28989333 Cogent M1 Tangential flow filtration Millipore Cat# CM06230 Pellicon 3 Cassette with Ultracel PLC Membrane Millipore Cat# P3C 010 C01 GenElute Plasmid Miniprep Kit Sigma-Aldrich Cat# PLN350 GenElute HP Plasmid Gigaprep Kit Sigma-Aldrich Cat# NA0800-1KT Qiagen Plasmid Mini kit Qiagen Cat# 12125 Mastercycler Nexus Gradient PCR Eppendorf Cat# 6331000068 Deposited Data Co-crystal structure of CD96-D1:necl-5 This paper PDB: 6ARQ Crystal structure of necl-5 (Harrison et al., 2012) PDB: 4FQP Experimental Models: Cell Lines Human: HEK293S GnTi- ATCC (In vitro Technologies) Cat# CRL-3022; RRID: CVCL_A785 Hi5 insect cells Life Technologies Cat# B855-02 Sf9 insect cells Thermo Fischer Scientific Cat# 11496-015 DH10Bac E.coli cells Thermo Fischer Scientific Cat# 10361-012 OneShot TOP10 chemical competent E.coli cells Thermo Fischer Scientific Cat# C404003 Recombinant DNA pHLSec (Aricescu et al., 2006) N/A pFastbac Thermo Fisher Scientific Cat# 10712-024 Synthetic genes for CD96 D1, nectin-2 and necl-5 IDT N/A (Continued on next page) Structure 27, 1–10.e1–e3, February 5, 2019 e1

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca 2+ -bound EFhd1 core domain (EFhd1 Ca ) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 m M ZnSO 4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Biochemical and crystallographic studies of l,d -transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate
Article Snippet: Ldt Mt2 wild type or Ldt Mt2 C354S (Δ1-55; with the N-terminal His Tag removed, in 50 mM tris, pH 8.0, 100 mM NaCl) was incubated with substrate 1 or for 30 minutes on ice, and then crystallised using a well solution consisting of 0.1 M HEPES, pH 7.0, and 25% ( v / v ) Jeffamine ED-2001 pH 7.0 (identified from the JCSG Plus TM crystallisation screen, Hampton Research), using sitting drop vapour diffusion crystallisation plates (low reservoir Intelli-Plate 93-3), with 1 μL of protein-substrate solution and 1 μL of well solution.

Article Title: Structural and biochemical insights into Zn<sup>2+</sup>-bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca2+-bound EFhd1 core domain (EFhd1Ca) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 mM ZnSO4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Structure and Function of Non-Native Metal Clusters in Human Arginase I
Article Snippet: Prepared solutions of 50% (w/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) and 30% (v/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) were purchased from Hampton Research (Aliso Viejo, CA).

In Vitro:

Article Title: Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys
Article Snippet: Diffraction-quality crystals of the DSM25/NKG2D SCD complex were obtained from drops containing 10 mg/mL protein in PNE by hanging-drop vapor diffusion over wells containing 100 mM HEPES (pH 7.2) and 35% w/w Jeffamine ED-2001 (Hampton Research #HR2-597).

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the former mixing solution, the Zn 2+ -bound EFhd1 core domain (EFhd1 Zn ) crystals were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 2.5 m M ZnSO 4 and 25%( w / v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural and Biochemical Characterization of EFhd1/Swiprosin-2, an Actin-Binding Protein in Mitochondria
Article Snippet: Crystals were obtained using a reservoir solution containing 0.1 M HEPES-NaOH (pH 7.5), 5 mM ZnSO 4 , and 25% (w/ v ) Jeffamine ED-2001 (Hampton Research).

Article Title: Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.
Article Snippet: REAGENT or RESOURCE SOURCE IDENTIFIER Chemicals, Peptides, and Recombinant Proteins CD96-D1 This paper N/A Necl-5 (Deuss et al., 2017) N/A Nectin-2 (Deuss et al., 2017) N/A DMEM High Glucose SOBS Media and Prep Services (Monash University) N/A Penicillin-Streptomycin-Glutamine (100X) Gibco Cat# 10378016 Glutamax (100X) Gibco Cat# 35050061 Non-essential Amino Acids (100X) Gibco Cat#11140050 FCS Sigma-Aldrich Cat# F9423 Insect-XPRESS medium Lonza Cat# 12-730Q Polyethyleneimine Sigma-Aldrich Cat# 408727 Cellfectin II Invitrogen Cat# 10362100 Endo H NEB Cat# P0702S D-biotin Sigma-Aldrich Cat# 47868 P20 GE Healthcare Cat# BR100054 Jeffamine ED-2001 Hampton Research Cat# HR2-597 HEPES Sigma-Aldrich Cat# H4034 PEG400 Sigma-Aldrich Cat# 202398 GoTaq Green master mix Promega Cat# M7123 Critical Commercial Assays Streptavidin coated chips GE Healthcare Cat# BR100032 HisTrap columns GE Healthcare Cat# 17-5248-02 Superdex200 16/600 column GE Healthcare Cat# 28989335 Superdex75 16/600 column GE Healthcare Cat# 28989333 Cogent M1 Tangential flow filtration Millipore Cat# CM06230 Pellicon 3 Cassette with Ultracel PLC Membrane Millipore Cat# P3C 010 C01 GenElute Plasmid Miniprep Kit Sigma-Aldrich Cat# PLN350 GenElute HP Plasmid Gigaprep Kit Sigma-Aldrich Cat# NA0800-1KT Qiagen Plasmid Mini kit Qiagen Cat# 12125 Mastercycler Nexus Gradient PCR Eppendorf Cat# 6331000068 Deposited Data Co-crystal structure of CD96-D1:necl-5 This paper PDB: 6ARQ Crystal structure of necl-5 (Harrison et al., 2012) PDB: 4FQP Experimental Models: Cell Lines Human: HEK293S GnTi- ATCC (In vitro Technologies) Cat# CRL-3022; RRID: CVCL_A785 Hi5 insect cells Life Technologies Cat# B855-02 Sf9 insect cells Thermo Fischer Scientific Cat# 11496-015 DH10Bac E.coli cells Thermo Fischer Scientific Cat# 10361-012 OneShot TOP10 chemical competent E.coli cells Thermo Fischer Scientific Cat# C404003 Recombinant DNA pHLSec (Aricescu et al., 2006) N/A pFastbac Thermo Fisher Scientific Cat# 10712-024 Synthetic genes for CD96 D1, nectin-2 and necl-5 IDT N/A (Continued on next page) Structure 27, 1–10.e1–e3, February 5, 2019 e1

Article Title: Structural and biochemical insights into Zn 2+ -bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca 2+ -bound EFhd1 core domain (EFhd1 Ca ) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 m M ZnSO 4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Biochemical and crystallographic studies of l,d -transpeptidase 2 from Mycobacterium tuberculosis with its natural monomer substrate
Article Snippet: Ldt Mt2 wild type or Ldt Mt2 C354S (Δ1-55; with the N-terminal His Tag removed, in 50 mM tris, pH 8.0, 100 mM NaCl) was incubated with substrate 1 or for 30 minutes on ice, and then crystallised using a well solution consisting of 0.1 M HEPES, pH 7.0, and 25% ( v / v ) Jeffamine ED-2001 pH 7.0 (identified from the JCSG Plus TM crystallisation screen, Hampton Research), using sitting drop vapour diffusion crystallisation plates (low reservoir Intelli-Plate 93-3), with 1 μL of protein-substrate solution and 1 μL of well solution.

Article Title: Structural and biochemical insights into Zn<sup>2+</sup>-bound EF-hand proteins, EFhd1 and EFhd2
Article Snippet: In the latter mixing solution, crystals of Ca2+-bound EFhd1 core domain (EFhd1Ca) were obtained using reservoir solution containing 0.1 M Tris–HCl (pH 8.5), 0.4 mM ZnSO4 and 25% Jeffamine ED-2001 (Hampton Research).

Article Title: Structure and Function of Non-Native Metal Clusters in Human Arginase I
Article Snippet: Prepared solutions of 50% (w/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) and 30% (v/v) Jeffamine ED-2001, 100 mM HEPES (pH 7.0) were purchased from Hampton Research (Aliso Viejo, CA).



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